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Author:
None
License:
GNU GENERAL PUBLIC LICENSE
Version 3, 29 June 2007
Copyright (C) 2007 Free Software Foundation, Inc. <https://fsf.org/>
Everyone is permitted ...
Summary:
SoNNia is a Python 3 software developed to infer selection pressures on features of amino acid CDR3 sequences. SoNNia takes as input TCR CDR3 amino acid sequences with V and J genes. Its output is sequence-level selection factors which indicate how more or less represented this sequence would be in the selected pool as compared to the pre-selected pool. These in turn could be used to calculate the probability of observing any sequence after selection and sample from the selected repertoire.
Latest version:
0.4.0
Required dependencies:
keras
|
matplotlib
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numpy
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olga
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pandas
|
polars
|
scipy
|
torch
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tqdm
|
typer
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